Alcohol Use Disorder Diagnoses and HIV Preexposure Prophylaxis Adherence and Continuation: a Retrospective Cohort Study - Takeaways - MDSpire

Alcohol Use Disorder Diagnoses and HIV Preexposure Prophylaxis Adherence and Continuation: a Retrospective Cohort Study

  • By

  • Anton L. V. Avanceña

  • Godwin Okoye

  • Rishit Yokananth

  • Aliza Norwood

  • Phillip W. Schnarrs

  • Jamie C. Barner

  • January 27, 2026

  • 0 min

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  • 1

    HIV diagnoses in the US have remained stable, highlighting the need for effective prevention strategies like pre-exposure prophylaxis (PrEP).

  • 2

    PrEP can reduce HIV risk by 99% with consistent use, but nonadherence significantly diminishes its protective effect.

  • 3

    Alcohol use disorder (AUD) is linked to lower adherence and continuation rates of PrEP among individuals at risk for HIV.

  • 4

    This study utilized real-world data to assess the impact of clinical AUD diagnoses on PrEP adherence and continuation.

  • 5

    Findings may inform guidelines for PrEP care and emphasize the need for interventions addressing both AUD and PrEP use.

Original Source(s)

Alcohol Use Disorder Diagnoses and HIV Preexposure Prophylaxis Adherence and Continuation: a Retrospective Cohort Study

  • by Anton L. V. Avanceña, Godwin Okoye, Rishit Yokananth, Aliza Norwood, Phillip W. Schnarrs, Jamie C. Barner

  • January 27, 2026

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