Kidney Morbidity in Pediatric Patients With Spina Bifida - Takeaways - MDSpire

Kidney Morbidity in Pediatric Patients With Spina Bifida

  • By

  • Hannah S. Thomas

  • Rano Matta

  • Samantha Morais

  • Drew Wilton

  • Refik Saskin

  • Michael Chua

  • Amanda Hird

  • Robert K. Nam

  • Sender Herschorn

  • Sarah Neu

  • June 26, 2026

  • 0 min

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  • 1

    The incidence of spina bifida varies globally, with 30 to 250 cases per 100,000 births, influenced by geographic location and folic acid access.

  • 2

    Approximately 88% of individuals with spina bifida survive to at least 25 years old, primarily based on data from high-income settings.

  • 3

    Advanced chronic kidney disease is twice as common in adults with spina bifida compared to those without, with earlier onset of end-stage renal disease.

  • 4

    An estimated 34% to 50% of pediatric patients with spina bifida develop chronic kidney disease, indicating a need for early identification.

  • 5

    The study aims to evaluate the incidence and age of onset of chronic kidney disease and end-stage renal disease in pediatric spina bifida patients.

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