Meta-analysis of the association between retinopathy and the risk of stroke - Takeaways - MDSpire

Meta-analysis of the association between retinopathy and the risk of stroke

  • By

  • Lingyun Wu

  • Weifeng Jiang

  • June 30, 2026

  • 0 min

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  • 1

    Retinopathy is associated with an increased risk of stroke, with a pooled odds ratio of 1.87 indicating significant correlation.

  • 2

    The meta-analysis included 23 studies, with 10 studies eligible for quantitative analysis, highlighting the relationship between retinopathy and stroke.

  • 3

    Subgroup analyses revealed a graded relationship between retinopathy severity and stroke risk, with higher risks in advanced stages.

  • 4

    Sensitivity analyses confirmed the robustness of findings, although a potential small-study effect could not be entirely excluded.

  • 5

    Retinal microvascular abnormalities may serve as a marker for cerebrovascular risk, but further validation in prospective studies is needed.

Original Source(s)

Meta-analysis of the association between retinopathy and the risk of stroke

  • by Lingyun Wu, Weifeng Jiang

  • June 30, 2026

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