An Investigation into the Impact of Various Intraoperative Disinfection Methods and Bacteriological Surveillance on Postoperative Intracranial Infection Rates Following Transnasal Endoscopic Skull Base Surgery

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Transnasal endoscopic skull base surgery (TESBS) is increasingly used for various skull base diseases due to its minimally invasive approach.
2

Intracranial infections post-TESBS occur in 0.8% to 7.98% of cases, primarily caused by non-pathogenic bacteria from the nasopharynx.
3

This study analyzed 1002 TESBS patients to compare the effectiveness of routine versus multiple intraoperative disinfection methods.
4

The multiple disinfection group had a lower intracranial infection rate (2.20%) compared to the routine disinfection group (5.72%).
5

Bacteriological monitoring during surgery revealed varying pathogenic bacteria, emphasizing the need for improved disinfection protocols.

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