Anxiety and depression and secondary prevention of coronary heart disease in 14 countries across six WHO regions: the INTERASPIRE study - Takeaways - MDSpire

Anxiety and depression and secondary prevention of coronary heart disease in 14 countries across six WHO regions: the INTERASPIRE study

  • By

  • Chantal F Ski

  • Catriona S Jennings

  • Dirk De Bacquer

  • Kornelia Kotseva

  • John William McEvoy

  • Guy De Backer

  • Iris Erlund

  • Sandra Ganly

  • Terhi Vihervaara

  • Gregory Yoke Hong Lip

  • Kausik K Ray

  • Lars Rydén

  • Agnieszka Adamska

  • Ana Abreu

  • Wael Almahmeed

  • Ade Meidian Ambari

  • Junbo Ge

  • Hosam Hasan-Ali

  • Yong Huo

  • Piotr Jankowski

  • Rodney M Jimenez

  • Yong Li

  • Ahmad Syadi Mahmood Zuhdi

  • Abel Makubi

  • Amam Chinyere Mbakwem

  • Lilian Mbau

  • Jose Luis Navarro Estrada

  • Okechukwu Samuel Ogah

  • Elijah Nyainda Ogola

  • Adalberto Quintero-Baiz

  • Mahmoud Umar Sani

  • Maria Ines Sosa Liprandi

  • Jack Wei Chieh Tan

  • Miguel Alberto Urina Triana

  • Tee Joo Yeo

  • David A Wood

  • David R Thompson

  • on behalf of the INTERASPIRE Investigators

  • November 13, 2025

  • 0 min

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  • 1

    Anxiety and depression are linked to poorer outcomes in coronary heart disease (CHD) patients, affecting secondary prevention standards.

  • 2

    Women with CHD exhibit higher prevalence and severity of anxiety and depression compared to men.

  • 3

    Increased severity of anxiety and depression symptoms correlates with lower odds of achieving recommended secondary prevention targets.

  • 4

    The INTERASPIRE study highlights the need for integrated management of mental health in CHD secondary prevention programs.

  • 5

    Holistic treatment approaches for CHD patients should consider both physical and mental health to improve overall outcomes.

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