Case Report: Exchange transfusion for hemolytic anemia and acute kidney injury associated with hepatic arterial infusion chemotherapy with raltitrexed and oxaliplatin in a patient with hepatocellular carcinoma - Takeaways - MDSpire

Case Report: Exchange transfusion for hemolytic anemia and acute kidney injury associated with hepatic arterial infusion chemotherapy with raltitrexed and oxaliplatin in a patient with hepatocellular carcinoma

  • By

  • Caili Zhang

  • Yajuan Yan

  • Xiaojian Li

  • Yong Dong

  • June 18, 2026

  • 0 min

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  • 1

    Hepatic arterial infusion chemotherapy with raltitrexed and oxaliplatin is increasingly accepted for advanced hepatocellular carcinoma treatment.

  • 2

    Oxaliplatin is associated with severe adverse reactions, including hemolytic anemia and acute kidney injury, particularly in colorectal cancer patients.

  • 3

    This case report documents the first instance of oxaliplatin-related hemolytic anemia and acute kidney injury in a hepatocellular carcinoma patient.

  • 4

    The patient achieved complete clinical resolution through two personalized sessions of exchange transfusion and artificial liver support therapy.

  • 5

    The report emphasizes the importance of recognizing and managing chemotherapy-associated complications in hepatocellular carcinoma patients.

Original Source(s)

Case Report: Exchange transfusion for hemolytic anemia and acute kidney injury associated with hepatic arterial infusion chemotherapy with raltitrexed and oxaliplatin in a patient with hepatocellular carcinoma

  • by Caili Zhang, Yajuan Yan, Xiaojian Li, Yong Dong

  • June 18, 2026

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