Case Report: Tuberculous meningitis presenting with multifocal cerebral infarction and hydrocephalus in a toddler - Takeaways - MDSpire

Case Report: Tuberculous meningitis presenting with multifocal cerebral infarction and hydrocephalus in a toddler

  • By

  • Camila S. Contreras-Rojas

  • Agilda Dema

  • Henry David

  • July 2, 2026

  • 0 min

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  • 1

    Tuberculous meningitis is a severe pediatric emergency with high rates of neurological disability due to hydrocephalus and inflammatory vasculopathy.

  • 2

    A 2-year-old boy presented with febrile illness and developed focal neurological deficits, with MRI revealing multiple unilateral acute infarcts.

  • 3

    Cerebrospinal fluid analysis showed lymphocytic pleocytosis and hypoglycorrhachia, supporting the diagnosis of tuberculous meningitis.

  • 4

    Follow-up imaging demonstrated rapid progression to bilateral infarcts, basilar leptomeningeal enhancement, and obstructive hydrocephalus.

  • 5

    The patient was treated with a four-drug antituberculosis regimen and corticosteroids, leading to clinical improvement after shunt placement.

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