Preoperative nTMS analysis: a sensitive tool to detect imminent motor deficits in brain tumor patients

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Navigated Transcranial Magnetic Stimulation (nTMS) enhances preoperative planning by localizing motor eloquent areas in brain tumor patients.
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Preoperative nTMS mapping correlates with more extensive tumor resections and reduced postoperative functional deficits.
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A regression model using nTMS data assesses individual risk for postoperative motor deficits based on tumor characteristics and neurophysiological parameters.
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The study included 170 patients with malignant glioma, evaluating anatomical tumor location and motor system excitability.
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Additional neurophysiological parameters, such as cortical silent period and recruitment curve, aim to improve prognostic power for motor outcomes.

Acta Neurochirurgica

by Ina Moritz, Melina Engelhardt, Tizian Rosenstock, Ulrike Grittner, Oliver Schweizerhof, Rutvik Khakhar, Heike Schneider, Andia Mirbagheri, Anna Zdunczyk, Katharina Faust, Peter Vajkoczy, Thomas Picht
October 21, 2024

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