Comparative Study on the Efficacy and Safety of Different Left Atrial Appendage Occluders in One-Stop Atrial Fibrillation Procedures - Takeaways - MDSpire

Comparative Study on the Efficacy and Safety of Different Left Atrial Appendage Occluders in One-Stop Atrial Fibrillation Procedures

  • By

  • Ren, Haoqiang

  • Lai, Hengli

  • May 8, 2026

  • 0 min

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  • 1

    The study compared the efficacy and safety of WATCHMAN, LAmbre, and LACBES occluders in atrial fibrillation treatment.

  • 2

    A total of 231 patients were analyzed, with 110 receiving WATCHMAN, 72 LAmbre, and 49 LACBES occluders.

  • 3

    Peri-device leak rates were 8.2% for WATCHMAN, 6.9% for LAmbre, and 4.1% for LACBES, with no significant differences.

  • 4

    A higher CHA₂DS₂-VASc score was identified as an independent risk factor for peri-device leaks.

  • 5

    The study concluded that all three occluders were similarly effective in LAA closure during the one-stop procedure.

Original Source(s)

Comparative Study on the Efficacy and Safety of Different Left Atrial Appendage Occluders in One-Stop Atrial Fibrillation Procedures

  • by Ren, Haoqiang , Lai, Hengli

  • May 8, 2026

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