Long-term outcome of patients with atrial fibrillation and heart failure with preserved ejection fraction after combined radiofrequency catheter ablation and left atrial appendage closure - Takeaways - MDSpire

Long-term outcome of patients with atrial fibrillation and heart failure with preserved ejection fraction after combined radiofrequency catheter ablation and left atrial appendage closure

  • By

  • Qian-ji Che

  • Yi-Chao Zhang

  • Mu Chen

  • Peng-cheng Yao

  • Qun-Shan Wang

  • Jian Sun

  • Wei Li

  • Bo Liu

  • Peng-Pai Zhang

  • Yi-Chi Yu

  • Yu-li Yang

  • Mei Yang

  • Rui Zhang

  • Yi-Gang Li

  • June 22, 2026

  • 0 min

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  • 1

    The study evaluated the long-term outcomes of combined radiofrequency catheter ablation and left atrial appendage closure in patients with AF and HFpEF.

  • 2

    A total of 331 patients were analyzed, with 196 receiving RF + LAAC and 135 receiving RF alone, after matching for propensity scores.

  • 3

    The RF + LAAC group had similar procedural complication rates compared to the RF group, with rates of 5.2% and 4.2%, respectively.

  • 4

    Patients in the RF + LAAC group experienced significantly lower risks of ischemic stroke/TIA and major bleeding compared to those receiving RF alone.

  • 5

    HF rehospitalization rates were similar between the RF + LAAC and RF groups, indicating no increase in rehospitalization with the combined procedure.

Original Source(s)

Long-term outcome of patients with atrial fibrillation and heart failure with preserved ejection fraction after combined radiofrequency catheter ablation and left atrial appendage closure

  • by Qian-ji Che, Yi-Chao Zhang, Mu Chen, Peng-cheng Yao, Qun-Shan Wang, Jian Sun, Wei Li, Bo Liu, Peng-Pai Zhang, Yi-Chi Yu, Yu-li Yang, Mei Yang, Rui Zhang, Yi-Gang Li

  • June 22, 2026

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