Successful Management of Seizures Through a Gluten-Free Diet in a Patient with Drug-Resistant Epilepsy and Celiac Disease: A Case Study - Takeaways - MDSpire

Successful Management of Seizures Through a Gluten-Free Diet in a Patient with Drug-Resistant Epilepsy and Celiac Disease: A Case Study

  • By

  • Hajer Hassine

  • Fatma Fatnassi

  • Chaima Jemai

  • Nesrine Krifa

  • Habiba Dabbebi

  • Souhir Monastiri

  • Haythem Yacoub

  • Dhouha Cherif

  • Nadia Maamouri

  • Hela Kchir

  • February 5, 2026

  • 0 min

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  • 1

    Celiac disease (CD) is an autoimmune disorder linked to various neurological conditions, including drug-resistant epilepsy.

  • 2

    The patient, diagnosed with cryptogenic drug-resistant epilepsy, was found to have undiagnosed celiac disease after extensive testing.

  • 3

    A gluten-free diet (GFD) was initiated, leading to significant improvements in seizure control and overall health.

  • 4

    After six months on a GFD, the patient remained seizure-free, with normalized metabolic parameters and improved quality of life.

  • 5

    This case highlights the importance of screening for celiac disease in patients with unexplained or refractory seizures.

Original Source(s)

Successful Management of Seizures Through a Gluten-Free Diet in a Patient with Drug-Resistant Epilepsy and Celiac Disease: A Case Study

  • by Hajer Hassine, Fatma Fatnassi, Chaima Jemai, Nesrine Krifa, Habiba Dabbebi, Souhir Monastiri, Haythem Yacoub, Dhouha Cherif, Nadia Maamouri, Hela Kchir

  • February 5, 2026

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