Geometric Patterns of the Left Ventricle and Systolic Function in Nigerian Pediatric Patients with Homozygous Sickle Cell Anemia - Takeaways - MDSpire

Geometric Patterns of the Left Ventricle and Systolic Function in Nigerian Pediatric Patients with Homozygous Sickle Cell Anemia

  • By

  • Igoche D. Peter

  • Mustafa O. Asani

  • Shehu U. Abdullahi

  • Ibrahim Aliyu

  • Josephat M. Chinawa

  • Stephen K. Obaro

  • Fidelia Bode-Thomas

  • January 8, 2026

  • 0 min

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  • 1

    Sickle cell anemia is a significant public health issue in sub-Saharan Africa, causing multiorgan complications, including cardiovascular issues in children.

  • 2

    The study compared left ventricular systolic function and geometry between 120 Nigerian pediatric patients with sickle cell anemia and matched controls.

  • 3

    Children with sickle cell anemia exhibited higher systolic blood pressure and lower oxygen saturation compared to healthy controls.

  • 4

    The study aimed to determine the prevalence of left ventricular systolic dysfunction and abnormal geometry in pediatric sickle cell anemia patients.

  • 5

    Findings indicated significant differences in clinical characteristics, with sickle cell patients showing lower hemoglobin and fetal hemoglobin levels.

Original Source(s)

Geometric Patterns of the Left Ventricle and Systolic Function in Nigerian Pediatric Patients with Homozygous Sickle Cell Anemia

  • by Igoche D. Peter, Mustafa O. Asani, Shehu U. Abdullahi, Ibrahim Aliyu, Josephat M. Chinawa, Stephen K. Obaro, Fidelia Bode-Thomas

  • January 8, 2026

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