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1
Peri-implantitis is a biofilm-mediated inflammatory condition with a prevalence of approximately 22%, leading to bone and soft tissue loss around dental implants.
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2
The pathogenesis of peri-implantitis involves dysregulated immune responses, altered tissue biology, and persistent microbial biofilm, complicating treatment predictability.
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3
Current treatment modalities include chemical and mechanical detoxification strategies, but no single method has shown consistent superiority in clinical outcomes.
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4
True re-osseointegration of dental implants remains difficult to achieve, often resulting in newly formed bone being separated from the implant surface.
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5
Future research should focus on long-term human outcomes and optimizing combined therapeutic protocols to enhance predictability and implant survival.
