Effect of weight loss intervention on assisted reproductive outcomes in women with obesity and infertility: a retrospective cohort study - Takeaways - MDSpire

Effect of weight loss intervention on assisted reproductive outcomes in women with obesity and infertility: a retrospective cohort study

  • By

  • Hua Dai

  • Qifeng He

  • Yongxin Liu

  • Ling Wu

  • Hongmei Wang

  • May 20, 2026

  • 0 min

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  • 1

    A retrospective cohort study evaluated the impact of a weight loss intervention on live birth rates in obese infertile women undergoing ART.

  • 2

    The Target-oriented Group achieved a mean weight reduction of 9.96%, while the Standard Lifestyle Group showed minimal change of 0.68%.

  • 3

    Live birth rates were significantly higher in the Target-oriented Group at 39.66% compared to 15.52% in the Standard Lifestyle Group.

  • 4

    The study found a higher likelihood of clinical pregnancy in the Target-oriented Group with an adjusted hazard ratio of 2.86.

  • 5

    The findings suggest that a structured weight loss intervention may improve reproductive outcomes in obese women, despite the study's retrospective design.

Original Source(s)

Effect of weight loss intervention on assisted reproductive outcomes in women with obesity and infertility: a retrospective cohort study

  • by Hua Dai, Qifeng He, Yongxin Liu, Ling Wu, Hongmei Wang

  • May 20, 2026

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