Adjusted Calcium Is Lying — And Labs Keep Printing It - Takeaways - MDSpire
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Adjusted Calcium Is Lying — And Labs Keep Printing It

Choy et al. argue it's time to stop trusting a number that's been unreliable for fifty years.

  • By

  • Kerri Miller

  • March 18, 2026

  • 1 min

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  • 1

    Albumin-adjusted calcium has significant limitations and remains widely used despite evidence against its reliability.

  • 2

    Adjusted calcium is particularly unreliable in elderly, critically ill, and renally impaired patients.

  • 3

    The editorial warns that universal use of albumin-adjusted calcium can lead to misdiagnosis of calcium disorders.

  • 4

    The concept of 'corrected calcium' has faced challenges since the 1970s, yet it persists in clinical practice.

  • 5

    The authors advocate for replacing albumin-adjusted calcium with ionised calcium as the preferred measurement.

Original Source(s)

Adjusted Calcium Is Lying — And Labs Keep Printing It

  • by Kerri Miller

  • March 18, 2026

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