Dermatologic Conditions and Incident Anxiety in Young Adults: Propensity Score–Matched Retrospective Cohort Study - Takeaways - MDSpire
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The Relationship Between Skin Disorders and the Development of Anxiety in Young Adults: A Retrospective Cohort Study Using Propensity Score Matching

  • By

  • Isabella Zai

  • Adrian Zai

  • June 3, 2026

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  • 1

    Dermatologic conditions are prevalent among adolescents and young adults, often impacting their mental health during critical developmental transitions.

  • 2

    Previous studies linking skin disorders to anxiety often rely on cross-sectional data, limiting their ability to establish temporal relationships.

  • 3

    This study utilized a large federated electronic health record network to assess the risk of incident anxiety following dermatologic diagnoses in young adults.

  • 4

    The study population included young adults aged 18 to 22 years with clinical encounters recorded between January 1, 2019, and December 31, 2020.

  • 5

    Propensity score matching was employed to create balanced cohorts for analyzing the association between dermatologic diagnoses and subsequent anxiety.

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