Worldwide Research Patterns and New Developments in Intratumoral Microbiota's Role in Cancer Immunotherapy: A Bibliometric and Visualization Study

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Intratumoral microbiota play a significant role in cancer immunotherapy by influencing the tumor immune microenvironment and responses to immune checkpoint inhibitors.
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The study analyzed 245 publications, revealing a compound annual growth rate of 63.1% in research on intratumoral microbiota from 2017 to 2024.
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China led in publication output, while the United States had the highest total citations and international collaboration in this research area.
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Keyword analysis identified 'intratumoral microbiota' as the most frequent term, indicating a shift towards immunotherapy resistance and microbiota-targeted interventions.
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The research landscape remains fragmented, necessitating systematic analyses to clarify developmental trajectories and identify future research directions.

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