Cognition-Affecting Drugs Often Start in Acute Care - Takeaways - MDSpire

Cognition-Affecting Drugs Often Start in Acute Care

  • By

  • Andrea Surnit

  • May 1, 2026

  • 3 min

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  • 1

    Cognitive risk drugs are often initiated in acute care settings, exceeding expected rates based on visit patterns.

  • 2

    The study analyzed 4955 new medication initiations among Medicare beneficiaries aged 66 and older from 2008 to 2021.

  • 3

    Persistence of cognitive risk medications one year after initiation was common, especially among patients with greater cognitive impairment.

  • 4

    Among patients with dementia, 67% continued antipsychotic treatment one year after initiation.

  • 5

    The study suggests targeting acute and postacute settings may effectively reduce prescriptions of cognition-impairing medications.

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