Cost-effectiveness of Alternative Approaches to Hepatitis C Diagnosis and Treatment Initiation for Treatment-naive People Who Inject Drugs in Australia: A Model-based Economic Evaluation - Takeaways - MDSpire

Cost-effectiveness of Alternative Approaches to Hepatitis C Diagnosis and Treatment Initiation for Treatment-naive People Who Inject Drugs in Australia: A Model-based Economic Evaluation

  • By

  • Christopher R Bailie

  • Nick Scott

  • Alisa E Pedrana

  • Margaret E Hellard

  • Joseph S Doyle

  • August 22, 2025

  • 0 min

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  • 1

    The study evaluated cost-effectiveness of seven hepatitis C diagnosis and treatment strategies for treatment-naive individuals who inject drugs in Australia.

  • 2

    Reflex laboratory antibody then RNA testing was the most cost-effective strategy, reducing average cost per treatment completion to $6141 AUD.

  • 3

    Point-of-care testing strategies improved treatment initiation but were more expensive, with costs ranging from $6976 to $11,707 AUD per completion.

  • 4

    Changes in treatment uptake of at least 16 points were necessary to equate reflex laboratory testing with point-of-care strategies.

  • 5

    The study highlights the need for innovative strategies to engage undiagnosed populations and optimize the hepatitis C care cascade.

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