Acute toxic encephalopathy induced by chloropicrin: case report - Takeaways - MDSpire

Acute toxic encephalopathy induced by chloropicrin: case report

  • By

  • Luye Wang

  • Yingzhan Jiang

  • Weiwei Yan

  • June 10, 2026

  • 0 min

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  • 1

    Chloropicrin is a highly toxic pesticide used for soil fumigation, primarily affecting the eyes, skin, and respiratory system.

  • 2

    A 53-year-old male developed toxic encephalopathy after exposure to chloropicrin, presenting with impaired consciousness and agitation.

  • 3

    The patient underwent extensive testing, including CT, MRI, and lumbar puncture, which ruled out other neurological conditions.

  • 4

    Supportive treatment included antioxidants and hyperbaric oxygen therapy, leading to improved consciousness after three weeks.

  • 5

    This case highlights the need for better protective measures for agricultural workers and increased awareness of chloropicrin's neurological risks.

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