Potential clinical value of circulating tumor cells in predicting progression for atypical teratoid rhabdoid tumor in young children - Takeaways - MDSpire

Potential clinical value of circulating tumor cells in predicting progression for atypical teratoid rhabdoid tumor in young children

  • By

  • Wei Zhang

  • Ke Cao

  • Xiaoling Zhang

  • Nianhua Cao

  • Lidan Xiao

  • Zongbin Liu

  • Xiuli Yuan

  • Jingsheng Wang

  • October 28, 2025

  • 0 min

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  • 1

    Atypical teratoid rhabdoid tumor (ATRT) is a highly malignant CNS tumor primarily affecting children under 3 years old.

  • 2

    Current ATRT treatment includes surgery, high-dose chemotherapy, and cautious use of radiotherapy due to neurocognitive risks.

  • 3

    Circulating tumor cells (CTCs) may predict tumor progression and assist in treatment planning for ATRT in pediatric patients.

  • 4

    The study evaluated the feasibility of detecting CTCs in cerebrospinal fluid and blood samples from children with ATRT.

  • 5

    Statistical analysis showed the potential of CTCs in assessing tumor progression, with significant results from various detection methods.

Original Source(s)

Potential clinical value of circulating tumor cells in predicting progression for atypical teratoid rhabdoid tumor in young children

  • by Wei Zhang, Ke Cao, Xiaoling Zhang, Nianhua Cao, Lidan Xiao, Zongbin Liu, Xiuli Yuan, Jingsheng Wang

  • October 28, 2025

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