Magnetic resonance imaging and clinical prediction of intracranial atherosclerotic large vessel occlusion in acute ischemic stroke treated with endovascular thrombectomy - Takeaways - MDSpire

Magnetic resonance imaging and clinical prediction of intracranial atherosclerotic large vessel occlusion in acute ischemic stroke treated with endovascular thrombectomy

  • By

  • Yohei Tateishi

  • Hiroaki Otsuka

  • Aya Yamashita

  • Keiichiro Onizuka

  • Takanori Amano

  • Daiji Torimura

  • Yuki Tomita

  • Takuro Hirayama

  • Tomoaki Shima

  • Shunsuke Yoshimura

  • Teiichiro Miyazaki

  • Yuki Matsunaga

  • Hajime Maeda

  • Akira Tsujino

  • May 22, 2026

  • 0 min

Share

  • 1

    Intracranial atherosclerosis-related large vessel occlusion (ICAS-LVO) is a significant cause of acute ischemic stroke, particularly in East Asian and minority populations.

  • 2

    This study developed an MRI- and clinical-based predictive score, the ICAS-M score, to identify ICAS-LVO in patients undergoing endovascular thrombectomy.

  • 3

    Among 335 patients, 44 (13%) were identified with ICAS-LVO, with absence of atrial fibrillation being a strong predictor of this condition.

  • 4

    The ICAS-M score demonstrated high discrimination for ICAS-LVO, achieving an area under the curve (AUC) of 0.940 during internal validation.

  • 5

    MRI markers such as multiple cortical infarcts and absence of susceptibility vessel signs were independently associated with ICAS-LVO.

Original Source(s)

Magnetic resonance imaging and clinical prediction of intracranial atherosclerotic large vessel occlusion in acute ischemic stroke treated with endovascular thrombectomy

  • by Yohei Tateishi, Hiroaki Otsuka, Aya Yamashita, Keiichiro Onizuka, Takanori Amano, Daiji Torimura, Yuki Tomita, Takuro Hirayama, Tomoaki Shima, Shunsuke Yoshimura, Teiichiro Miyazaki, Yuki Matsunaga, Hajime Maeda, Akira Tsujino

  • May 22, 2026

Related Content

2026 Brain and Spine Symposium Highlights Advances Across the Neurosciences

Over two days, specialists across neurology, neurosurgery and related subspecialties came together to discuss advances in stroke care, epilepsy, movement disorders, neurodegenerative disease, neuro-oncology, brain and spine surgery, interventional pain management and emerging technologies.

  • by

  • May 21, 2026

  • 1 min
Editorial: Diffusion-weighted imaging: advances and implementations in neurology

Case Report: Neuronal intranuclear inclusion disease mimicking recurrent stroke in the setting of intracranial stenosis