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May Lower RFR Signal Repeat Revascularization?

Patients with lower nonischemic resting full-cycle ratio values had more repeat revascularizations despite similar 2-year major cardiovascular event rates.

  • By

  • Andrea Surnit

  • July 28, 2026

  • 4 min

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  • 1

    Deferring coronary revascularization based on nonischemic resting full-cycle ratio (RFR) may lead to favorable 2-year cardiovascular outcomes.

  • 2

    Patients with lower nonischemic RFR values underwent repeat revascularization more frequently compared to those with higher values.

  • 3

    The study evaluated 773 patients with 1,012 angiographically intermediate coronary lesions from 2016 to 2022.

  • 4

    At 2 years, the lesion-based major adverse cardiovascular event (MACE) rate was 8%, with no significant differences across RFR groups.

  • 5

    Chronic obstructive pulmonary disease was independently associated with higher rates of MACE following multivariable adjustment.

Original Source(s)

May Lower RFR Signal Repeat Revascularization?

  • by Andrea Surnit

  • July 28, 2026

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