Smaller cingulate grey matter mediates the association between dual-task gait and incident dementia - Takeaways - MDSpire

Smaller cingulate grey matter mediates the association between dual-task gait and incident dementia

  • By

  • Pauline Ali

  • Frederico Pieruccini-Faria

  • Cédric Annweiler

  • Mickaël Dinomais

  • Surim Son

  • Scott K Wilson

  • Richard Camicioli

  • Susan Muir-Hunter

  • Robert Bartha

  • Manuel Montero-Odasso

  • November 5, 2024

  • 0 min

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  • 1

    Individuals with mild cognitive impairment and high dual-task gait cost are three times more likely to progress to dementia.

  • 2

    Smaller grey matter volume in the right anterior and middle cingulate cortices mediates the link between dual-task cost and incident dementia.

  • 3

    High dual-task cost during cognitive tasks correlates with increased risk of dementia, particularly when counting backwards or naming animals.

  • 4

    The study followed 139 participants over nine years, with 24% progressing to dementia, highlighting the importance of monitoring gait performance.

  • 5

    Dual-task gait tests may serve as a reliable biomarker for early detection and monitoring of dementia in individuals with mild cognitive impairment.

Original Source(s)

Smaller cingulate grey matter mediates the association between dual-task gait and incident dementia

  • by Pauline Ali, Frederico Pieruccini-Faria, Cédric Annweiler, Mickaël Dinomais, Surim Son, Scott K Wilson, Richard Camicioli, Susan Muir-Hunter, Robert Bartha, Manuel Montero-Odasso

  • November 5, 2024

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