High versus low ligation of the inferior mesenteric artery during transanal total mesorectal excision for low rectal cancer: impact on postoperative anastomotic leakage - Takeaways - MDSpire

High versus low ligation of the inferior mesenteric artery during transanal total mesorectal excision for low rectal cancer: impact on postoperative anastomotic leakage

  • By

  • Junfeng Du

  • Chen Su

  • Xiang Xu

  • Lanxin Hu

  • Xuefei Zhang

  • Hongyu Zhang

  • July 16, 2026

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  • 1

    The study compared LCA-preserving low ligation and high ligation of the inferior mesenteric artery in low rectal cancer patients.

  • 2

    Postoperative anastomotic leakage was significantly lower in the LCA preservation group compared to the non-preservation group (4.3% vs. 13.2%).

  • 3

    Among patients receiving neoadjuvant therapy, LCA preservation was associated with lower anastomotic leakage rates (7.0% vs. 24.0%).

  • 4

    The study included 182 patients with low rectal cancer after propensity score matching from an initial cohort of 226.

  • 5

    No unified guidelines exist regarding LCA preservation during TME, highlighting the need for further research in this area.

Original Source(s)

High versus low ligation of the inferior mesenteric artery during transanal total mesorectal excision for low rectal cancer: impact on postoperative anastomotic leakage

  • by Junfeng Du, Chen Su, Xiang Xu, Lanxin Hu, Xuefei Zhang, Hongyu Zhang

  • July 16, 2026

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