Risk Assessment and Clinical Management of Peripheral Retinal Degenerations: Insights from Multimodal Imaging Techniques

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Peripheral retinal degenerations (PRD) range from benign atrophic changes to high-risk tractional lesions associated with retinal tears and detachment.
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Posterior vitreous detachment (PVD) is a key factor linking PRD to retinal tears and rhegmatogenous retinal detachment, especially during acute symptoms.
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Ultra-widefield imaging and swept-source OCT enhance visualization of peripheral retinal morphology, aiding in the differentiation of benign and unstable lesions.
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Selective prophylactic laser photocoagulation is supported for symptomatic retinal tears and confirmed tractional instability, while asymptomatic low-risk PRD need no routine treatment.
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Management of PRD should be individualized, utilizing multimodal imaging and clinical assessment to target interventions based on tractional instability and risk factors.

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