A systematic review of obesity prevalence and its contributing factors among individuals diagnosed with schizophrenia - Takeaways - MDSpire

A systematic review of obesity prevalence and its contributing factors among individuals diagnosed with schizophrenia

  • By

  • Jianmei Long

  • Bo Yang

  • Qiong Zheng

  • April 27, 2026

  • 0 min

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  • 1

    The meta-analysis included 18 studies with 9,351 patients, revealing an obesity incidence of 33.0% among individuals with schizophrenia.

  • 2

    Significant risk factors for obesity in schizophrenia patients include female sex, diabetes, and the use of various antipsychotic medications.

  • 3

    Olanzapine use was associated with the highest odds of obesity (OR = 7.40), indicating a strong link between this medication and weight gain.

  • 4

    The study emphasizes the need for early screening and targeted interventions to address obesity in patients with schizophrenia.

  • 5

    Obesity in schizophrenia patients is linked to increased healthcare costs and a higher risk of metabolic disorders, impacting overall quality of life.

Original Source(s)

A systematic review of obesity prevalence and its contributing factors among individuals diagnosed with schizophrenia

  • by Jianmei Long, Bo Yang, Qiong Zheng

  • April 27, 2026

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