Visit-to-visit blood pressure variability and cardiovascular outcomes: a systematic review and dose-response meta-analysis - Takeaways - MDSpire

Visit-to-visit blood pressure variability and cardiovascular outcomes: a systematic review and dose-response meta-analysis

  • By

  • Mifetika Lukitasari

  • Jitendra Jonnagaddala

  • Siaw-Teng Liaw

  • Bin Jalaludin

  • August 28, 2025

  • 0 min

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  • 1

    Visit-to-visit blood pressure variability (VVV BPV) is an independent risk factor for cardiovascular disease (CVD) that is often overlooked in clinical practice.

  • 2

    A systematic review and meta-analysis of 49 studies found that VVV BPV is linked to increased CVD risk, with effect sizes similar between EHR and non-EHR data.

  • 3

    A standard deviation of VVV BPV ≥6.72 mmHg or a coefficient of variation ≥9.05% is associated with a 10% higher risk of cardiovascular events.

  • 4

    The reliability of electronic health records (EHR) in estimating VVV BPV is comparable to non-EHR sources, suggesting EHR can be used for CVD risk evaluation.

  • 5

    Further research is needed to improve the integration of VVV BPV assessment into clinical workflows to enhance cardiovascular risk management.

Original Source(s)

Visit-to-visit blood pressure variability and cardiovascular outcomes: a systematic review and dose-response meta-analysis

  • by Mifetika Lukitasari, Jitendra Jonnagaddala, Siaw-Teng Liaw, Bin Jalaludin

  • August 28, 2025

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