Association of the inflammatory burden index with 1-year major adverse cardiovascular events in patients with HFpEF after myocardial infarction: a single-center retrospective cohort study - Takeaways - MDSpire

Association of the inflammatory burden index with 1-year major adverse cardiovascular events in patients with HFpEF after myocardial infarction: a single-center retrospective cohort study

  • By

  • Xiaoyan Yin

  • Pan Chen

  • Boshi Liu

  • Lei Ren

  • June 10, 2026

  • 0 min

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  • 1

    The study evaluated the association between the Inflammatory Burden Index (IBI) and 1-year major adverse cardiovascular events (MACE) in HFpEF patients post-myocardial infarction.

  • 2

    A total of 592 patients with HFpEF and documented myocardial infarction were included in the retrospective cohort analysis.

  • 3

    Higher log-transformed IBI was independently linked to an increased risk of 1-year MACE, with a hazard ratio of 1.828.

  • 4

    Incorporating logIBI into the clinical model improved risk discrimination, raising the 365-day AUC from 0.790 to 0.832.

  • 5

    The findings suggest that IBI may serve as a practical measure of inflammatory burden in HFpEF patients, pending further validation.

Original Source(s)

Association of the inflammatory burden index with 1-year major adverse cardiovascular events in patients with HFpEF after myocardial infarction: a single-center retrospective cohort study

  • by Xiaoyan Yin, Pan Chen, Boshi Liu, Lei Ren

  • June 10, 2026

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