Assessment of Corneal Optical Densitometry and Anterior Segment Characteristics in a Healthy Upper Egyptian Cohort: A Prospective Observational Cross-Sectional Analysis - Takeaways - MDSpire
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Assessment of Corneal Optical Densitometry and Anterior Segment Characteristics in a Healthy Upper Egyptian Cohort: A Prospective Observational Cross-Sectional Analysis

  • By

  • Mohamed A. Hamid

  • Mohamed Esmail Khalil Esmail

  • Hosny A. Zein

  • December 1, 2025

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  • 1

    The study assessed corneal optical densitometry (COD) and anterior segment characteristics in a healthy Upper Egyptian cohort.

  • 2

    Corneal optical densitometry measures light scattering in the cornea, with higher values indicating reduced transparency.

  • 3

    The study included 379 subjects aged 16 to 73, with a mean spherical equivalent of -2.1 D and a mean central corneal thickness of 523.7 µm.

  • 4

    Scheimpflug imaging via the Oculus Pentacam was utilized to evaluate COD across different corneal zones and layers.

  • 5

    The findings highlight the need for region-specific studies to understand corneal health in diverse populations.

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