Stress Hyperglycemia Ratio and the Risk of Sepsis in Patients With Heart Failure: Retrospective Cohort Study From Medical Information Mart for Intensive Care-IV - Takeaways - MDSpire

Stress Hyperglycemia Ratio and the Risk of Sepsis in Patients With Heart Failure: Retrospective Cohort Study From Medical Information Mart for Intensive Care-IV

  • By

  • Xianzhen Cai

  • Baoxin Yan

  • Jinhao Chen

  • Junjun Ye

  • Jiating Su

  • Shuangshuang Tong

  • Bin Xie

  • Bingna Zhang

  • Jilin Li

  • April 17, 2026

  • 0 min

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  • 1

    Heart failure (HF) has a rising global prevalence and is associated with a high risk of mortality and rehospitalization.

  • 2

    Patients with HF are at increased risk for sepsis, with a threefold higher recurrence rate compared to those without HF.

  • 3

    Stress hyperglycemia ratio (SHR) may serve as a valuable metric for assessing acute glycemic levels and sepsis risk in HF patients.

  • 4

    The study utilized the MIMIC-IV database to investigate the association between SHR and sepsis occurrence in critically ill HF patients.

  • 5

    Inflammation may mediate the relationship between SHR and sepsis risk, highlighting the need for further research in this area.

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