Bilateral distal femoral sclerotic lesions in elderly women: a distinct benign imaging pattern associated with fat necrosis and dystrophic calcification - Takeaways - MDSpire
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A Benign Bilateral Distal Femoral Sclerosis Pattern in Older Women Linked to Fat Necrosis and Dystrophic Calcification

  • By

  • Caroline Chabot

  • Jacques Malghem

  • Anthony Lichaa

  • Lokmane Taihi

  • Christine Galant

  • Donald Resnick

  • Bruno Vande Berg

  • October 7, 2026

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  • 1

    The study describes a bilateral, nonaggressive pattern of intramedullary sclerosis in the distal femoral metadiaphyses of older women.

  • 2

    Lesions were round or elongated and showed no cortical erosion, periosteal reaction, or soft-tissue extension.

  • 3

    The retrospective, bicentric study assessed clinical data and radiographic, CT, and MRI findings in patients with the pattern.

  • 4

    Clinical and laboratory measures were compared with those of 30 age- and sex-matched controls without femoral lesions.

  • 5

    The study also assessed the pattern’s prevalence using consecutive full-length lower-limb EOS radiographs obtained at one institution from 2021 through 2023.

Original Source(s)

Bilateral distal femoral sclerotic lesions in elderly women: a distinct benign imaging pattern associated with fat necrosis and dystrophic calcification

  • by Caroline Chabot, Jacques Malghem, Anthony Lichaa, Lokmane Taihi, Christine Galant, Donald Resnick, Bruno Vande Berg

  • October 7, 2026

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