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1
Transcranial direct current stimulation (tDCS) significantly improves global cognition in patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI).
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2
The meta-analysis included 13 studies with a total of 616 participants, demonstrating a standardized mean difference (SMD) of 0.49 for global cognition improvement.
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3
Preliminary evidence suggests tDCS may enhance visuospatial abilities, with an SMD of -0.75, but findings for attention and executive function are inconclusive.
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4
tDCS is a non-invasive, safe, and affordable neuromodulation technique that can be administered at home, increasing accessibility for patients.
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5
Future research should utilize multi-test, domain-specific neuropsychological batteries in adequately powered trials to further assess tDCS efficacy.
