Nonexudative Macular Neovascularization in Age-Related Macular Degeneration - Takeaways - MDSpire

Nonexudative Macular Neovascularization in Age-Related Macular Degeneration

  • By

  • Sridevi Thottarath

  • Sarega Gurudas

  • Syed Kubravi

  • Dimitrios Kazantzis

  • Ayse Merve Keskin

  • Sobha Sivaprasad

  • EYENEON Study Group

  • Benjamin Burton

  • Geeta Menon

  • Manju Chandran

  • Ian Pearce

  • Savita Madhusudhan

  • Anna Grabowska

  • Faruque Ghanchi

  • James Talks

  • Richard Gale

  • Martin McKibbin

  • Ajay Kotagiri

  • Niro Narendran

  • Afsar Jafree

  • Saad Younis

  • Claire Bailey

  • Priya Prakash

  • Christiana Dinah

  • Louise Downey

  • Andrew Lottery

  • Paritosh Shah

  • Romi Chhabra

  • Narendra Dhingra

  • Indra Dias

  • Mary Freeman

  • Daren Hanumunthadu

  • May 1, 2026

  • 0 min

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  • 1

    Subclinical nonexudative macular neovascularization (neMNV) is a significant risk factor for exudative age-related macular degeneration (nAMD).

  • 2

    The prevalence of neMNV in fellow eyes of unilateral exudative AMD patients varies widely, ranging from 6.25% to 27.00% based on study timing.

  • 3

    Double-layer sign (DLS) on optical coherence tomography (OCT) is often evaluated as a surrogate for neMNV, but its reliability is uncertain.

  • 4

    The EYENEON study aimed to assess the prevalence of neMNV and DLS in fellow eyes of patients with unilateral new-onset exudative nAMD.

  • 5

    The study included patients aged 50 to 100 years with unilateral treatment-naive exudative nAMD and utilized OCT and OCT-A for imaging.

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