Attenuation value of non-contrast computed tomography for spontaneous intracerebral hemorrhage: an important marker for the rapid identification of hematoma expansion - Takeaways - MDSpire

The Role of Non-Contrast CT Attenuation Values in Predicting Hematoma Expansion in Spontaneous Intracerebral Hemorrhage

  • By

  • Jing Wang

  • Chuyue Wu

  • Jing Guo

  • Zhenjie Yang

  • Lei He

  • Shengli Chen

  • Lina Zhang

  • July 17, 2026

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  • 1

    The study included 351 patients with spontaneous intracerebral hemorrhage (sICH) treated between January 2020 and December 2023.

  • 2

    Of the patients, 91 (25.9%) exhibited early hematoma expansion (HE) within the study period.

  • 3

    A relative CT attenuation value of 33.35 Hounsfield units (HUs) was identified as the critical threshold for predicting HE.

  • 4

    Multivariate logistic regression analysis indicated that relative CT attenuation value could independently predict HE (p = 0.006).

  • 5

    The study found a sensitivity of 40.9% and specificity of 83.1% for predicting HE with a relative CT attenuation value of ≤33.35 HU.

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