Case Report: Sapho syndrome complicated by chest pain successfully treated with relocation - Takeaways - MDSpire

Case Report: Sapho syndrome complicated by chest pain successfully treated with relocation

  • By

  • Youjun Zhang

  • Hongjin Chen

  • Shaofeng Guan

  • Xinkai Qu

  • June 2, 2026

  • 0 min

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  • 1

    SAPHO syndrome is a rare chronic autoinflammatory disease characterized by cutaneous and osteoarticular manifestations.

  • 2

    Diagnosis of SAPHO syndrome is based on clinical features and imaging findings, as validated diagnostic criteria are lacking.

  • 3

    The case study reports a 60-year-old woman with chest pain and plantar pustules diagnosed with SAPHO syndrome.

  • 4

    Environmental modification, including relocating to a drier environment, significantly relieved the patient's symptoms.

  • 5

    The study suggests shared environmental exposures may contribute to the development of immune diseases in cohabiting individuals.

Original Source(s)

Case Report: Sapho syndrome complicated by chest pain successfully treated with relocation

  • by Youjun Zhang, Hongjin Chen, Shaofeng Guan, Xinkai Qu

  • June 2, 2026

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