Association of Low Prognostic Nutritional Index Score with Lymph Node Metastasis in Breast Cancer Patients, Unlike Hemoglobin-Albumin-Lymphocyte-Platelet Score - Takeaways - MDSpire

Association of Low Prognostic Nutritional Index Score with Lymph Node Metastasis in Breast Cancer Patients, Unlike Hemoglobin-Albumin-Lymphocyte-Platelet Score

  • By

  • Weihua Wen

  • Litao Jin

  • Yuyang Yang

  • Jianjuan Li

  • April 27, 2026

  • 0 min

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  • 1

    The study involved 799 breast cancer patients to assess the relationship between PNI, HALP scores, and lymph node metastasis.

  • 2

    Low PNI scores were significantly associated with lymph node metastasis, while HALP scores showed no such correlation.

  • 3

    Median PNI and HALP scores were lower in patients with lymph node metastasis compared to those without.

  • 4

    Logistic regression indicated that low PNI levels are a potential risk factor for lymph node metastasis in breast cancer.

  • 5

    PNI can serve as a practical tool for predicting lymph node metastasis and guiding nutritional interventions in breast cancer patients.

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