Exploring the feasibility of modeling next-day fatigue and sleepiness using digital sleep tracker data in neurodegenerative and immune-mediated inflammatory diseases - Takeaways - MDSpire

Exploring the feasibility of modeling next-day fatigue and sleepiness using digital sleep tracker data in neurodegenerative and immune-mediated inflammatory diseases

  • By

  • Bing Zhai

  • Luan Chen

  • Xujun Ma

  • Clémence Pinaud

  • Meenakshi Chatterjee

  • Juha M. Kortelainen

  • Rana Zia Ur Rehman

  • Teemu Ahmaniemi

  • Stefan Avey

  • Yu Guan

  • Victoria Macrae

  • Chloe Hinchliffe

  • Silvia Del Din

  • Nikolay V. Manyakov

  • Robert Göder

  • Robbin Romijnders

  • Walter Maetzler

  • Ralf Reilmann

  • Svenja Aufenberg

  • Robin Schubert

  • C. Janneke van der Woude

  • Daqing Zhang

  • Wan-Fai Ng

  • June 17, 2026

  • 0 min

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  • 1

    Fatigue and sleep disturbances are prevalent in neurodegenerative diseases and immune-mediated inflammatory diseases.

  • 2

    Digital sleep trackers can provide objective monitoring of sleep and physiology, potentially improving fatigue prediction.

  • 3

    The study involved 134 participants and evaluated the predictive capacity of sleep features for next-day fatigue.

  • 4

    Preliminary results indicated moderate predictive performance for physical fatigue in healthy adults and NDD patients.

  • 5

    Further research is needed to establish disease-specific digital fatigue endpoints in chronic disease populations.

Original Source(s)

Exploring the feasibility of modeling next-day fatigue and sleepiness using digital sleep tracker data in neurodegenerative and immune-mediated inflammatory diseases

  • by Bing Zhai, Luan Chen, Xujun Ma, Clémence Pinaud, Meenakshi Chatterjee, Juha M. Kortelainen, Rana Zia Ur Rehman, Teemu Ahmaniemi, Stefan Avey, Yu Guan, Victoria Macrae, Chloe Hinchliffe, Silvia Del Din, Nikolay V. Manyakov, Robert Göder, Robbin Romijnders, Walter Maetzler, Ralf Reilmann, Svenja Aufenberg, Robin Schubert, C. Janneke van der Woude, Daqing Zhang, Wan-Fai Ng

  • June 17, 2026

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