Comparative Analysis of Medical and Surgical Interventions on Intraocular Pressure Variability in Glaucoma Patients at the University of Ilorin Teaching Hospital - Takeaways - MDSpire
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Comparative Analysis of Medical and Surgical Interventions on Intraocular Pressure Variability in Glaucoma Patients at the University of Ilorin Teaching Hospital

  • By

  • Tokunbo Sarah Obajolowo

  • Ibrahim Abiodun Yusuf

  • Ambali Olamilekan Ambali

  • Biola Toibat Tota-Bolarinwa

  • Azeezat Bola Aderounmu

  • Fatai Olasunkanmi Olatunji

  • January 22, 2026

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  • 1

    Glaucoma is a leading cause of irreversible blindness, affecting 67 million people globally, with higher prevalence in individuals of African descent.

  • 2

    Effective glaucoma management focuses on reducing intraocular pressure (IOP) through medications, laser treatments, and surgical procedures.

  • 3

    A significant number of glaucoma patients experience progression despite achieving target IOP, often due to diurnal IOP fluctuations.

  • 4

    This study compares IOP peaks and fluctuations between medically treated patients and those who underwent trabeculectomy in a Nigerian setting.

  • 5

    Results indicate that trabeculectomy provides superior IOP stability with lower peak and fluctuation values compared to medical therapy.

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