A Rare Case of Primary Angiomyofibroma of Soft Tissue in the Small Intestine Complicated by Intussusception: Case Report and Literature Review - Takeaways - MDSpire

A Rare Case of Primary Angiomyofibroma of Soft Tissue in the Small Intestine Complicated by Intussusception: Case Report and Literature Review

  • By

  • Min Liu

  • Yajing Sun

  • Shoufeng Wang

  • Zhongmin Jiang

  • February 9, 2026

  • 0 min

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  • 1

    Angiomyofibroma of soft tissue (AFST) is a rare, benign neoplasm primarily found in extremities, with no prior cases reported in the small intestine.

  • 2

    The presented case involved a 43-year-old male with AFST causing intussusception, leading to surgical intervention and resection of the affected segment.

  • 3

    Histological examination revealed uniform spindle cells within a branching vascular network, consistent with the characteristics of AFST.

  • 4

    Immunohistochemical analysis showed tumor cells positive for CD68 and CD163, aiding in the diagnosis of AFST despite its nonspecific profile.

  • 5

    Complete surgical excision is recommended for AFST, as local recurrence may occur, but distant metastases have not been reported.

Original Source(s)

A Rare Case of Primary Angiomyofibroma of Soft Tissue in the Small Intestine Complicated by Intussusception: Case Report and Literature Review

  • by Min Liu, Yajing Sun, Shoufeng Wang, Zhongmin Jiang

  • February 9, 2026

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