Comparative Analysis of Efficacy and Safety Between Pulsed Field Ablation and Very High-Power Short-Duration Ablation for Atrial Fibrillation: A Meta-Analytical Study

1

Pulsed field ablation (PFA) and very high power short duration ablation (vHPSD) are emerging techniques for catheter ablation of atrial fibrillation.
2

The meta-analysis included 11 observational studies with 1,476 patients, showing no significant difference in recurrence rates between PFA and vHPSD.
3

There was no significant difference in the rate of pulmonary vein isolation or total incidence of surgery-related complications between the two groups.
4

PFA demonstrated a shorter procedure time but longer fluoroscopy time compared to vHPSD, with significant differences in both metrics.
5

The study calls for more randomized controlled trials with larger sample sizes and longer follow-up to further verify the findings.

1