A higher monocyte-to-lymphocyte ratio is correlated with impaired glomerular function and adverse cardiac remodeling in elderly patients with atrial fibrillation: a retrospective study - Takeaways - MDSpire

A higher monocyte-to-lymphocyte ratio is correlated with impaired glomerular function and adverse cardiac remodeling in elderly patients with atrial fibrillation: a retrospective study

  • By

  • Xinrui Chen

  • Gang Li

  • Henri Mustonen

  • Jari A. Laukkanen

  • Linping Wei

  • Yufeng Li

  • July 7, 2026

  • 0 min

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  • 1

    A study analyzed 1,154 elderly patients with atrial fibrillation to investigate the relationship between monocyte-to-lymphocyte ratio and cardiac remodeling.

  • 2

    High monocyte-to-lymphocyte ratio (> 0.460) was independently linked to decreased estimated glomerular filtration rate and lower plasma albumin levels.

  • 3

    The study found that high monocyte-to-lymphocyte ratio was associated with male sex and adverse cardiac remodeling in elderly patients with atrial fibrillation.

  • 4

    Patients were categorized into low, moderate, and high monocyte-to-lymphocyte ratio groups based on tertiles for analysis.

  • 5

    The research was conducted in accordance with ethical standards and included patients aged 65 years and older with non-valvular atrial fibrillation.

Original Source(s)

A higher monocyte-to-lymphocyte ratio is correlated with impaired glomerular function and adverse cardiac remodeling in elderly patients with atrial fibrillation: a retrospective study

  • by Xinrui Chen, Gang Li, Henri Mustonen, Jari A. Laukkanen, Linping Wei, Yufeng Li

  • July 7, 2026

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