Case Report: Amiodarone-triggered refractory ventricular fibrillation storm in septic cardiomyopathy with pre-existing QT prolongation: termination using lidocaine and anisodamine - Takeaways - MDSpire

Case Report: Amiodarone-triggered refractory ventricular fibrillation storm in septic cardiomyopathy with pre-existing QT prolongation: termination using lidocaine and anisodamine

  • By

  • Min Wu

  • Lutao Xie

  • Pin Lan

  • Meisong Chen

  • June 10, 2026

  • 0 min

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  • 1

    Septic cardiomyopathy can lead to life-threatening arrhythmias like TdP and VF, especially with QT-prolonging medications.

  • 2

    An 89-year-old male developed refractory TdP and VF after receiving moxifloxacin and amiodarone for septic cardiomyopathy.

  • 3

    Standard treatments including defibrillation and electrolyte correction were ineffective in controlling the arrhythmias.

  • 4

    Intravenous lidocaine combined with anisodamine successfully terminated the refractory arrhythmias in this patient.

  • 5

    The patient showed significant recovery of cardiac function after treatment, highlighting the potential of this therapeutic approach.

Original Source(s)

Case Report: Amiodarone-triggered refractory ventricular fibrillation storm in septic cardiomyopathy with pre-existing QT prolongation: termination using lidocaine and anisodamine

  • by Min Wu, Lutao Xie, Pin Lan, Meisong Chen

  • June 10, 2026

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