Vascular health has an impact on brain health By Masud Husain May 13, 2025 0 min Brain Share Summary Takeaways Listen Insight Report Clinical Scorecard Quiz Poll Top Institutions 1 Optimizing vascular health may improve brain health and cognitive function, particularly in individuals with hypertension. 2 Antihypertensive treatment can significantly reduce the risk of dementia, especially in individuals with untreated hypertension. 3 Low-density lipoprotein (LDL) cholesterol levels below 1.8 mmol/l are associated with reduced dementia risk. 4 GLP-1 receptor agonists and SGLT2 inhibitors are linked to decreased incidence of Alzheimer's disease dementia in type 2 diabetes. 5 Targeting vascular risk factors like blood pressure and cholesterol may offer cost-effective strategies to reduce dementia risk.