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Development and evaluation of a preliminary risk assessment model for psychological distress among patients with brain tumors: a cross-sectional analysis

  • By

  • Ying Li

  • Yuyu Duan

  • Yangmei Su

  • Zhiman Zheng

  • Dongqi Zou

  • Zhihuan Zhou

  • January 22, 2026

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  • 1

    Brain tumors significantly impact patients' quality of life, with 44.5% to 76.0% experiencing clinically significant psychological distress.

  • 2

    Financial toxicity correlates strongly with psychological distress in brain tumor patients, exacerbating anxiety and depression.

  • 3

    Self-efficacy is inversely related to psychological distress, with higher self-efficacy linked to better coping and quality of life.

  • 4

    Adaptive coping strategies, such as seeking social support, can mitigate psychological distress in brain tumor patients.

  • 5

    The study developed a predictive model for psychological distress, focusing on financial toxicity, self-efficacy, and coping strategies.

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