Dual-Site aiTBS for Suicidal Ideation in Adolescents With Major Depressive Disorder: A Randomized Clinical - Takeaways - MDSpire

Dual-Site aiTBS for Suicidal Ideation in Adolescents With Major Depressive Disorder: A Randomized Clinical

  • By

  • Dong Huang

  • Rongxu Zhang

  • Shunkai Lai

  • Xiaojie Ye

  • Munila Abula

  • Xiaodong Song

  • Peiying Cao

  • Yiliang Zhang

  • Jianzhao Zhang

  • Shuming Zhong

  • Yanbin Jia

  • May 19, 2026

  • 0 min

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  • 1

    Adolescent suicide rates linked to major depressive disorder (MDD) have significantly increased, highlighting the need for effective interventions.

  • 2

    Accelerated intermittent theta burst stimulation (aiTBS) targeting both the left DLPFC and cerebellum shows promise in reducing suicidal ideation in adolescents with MDD.

  • 3

    A randomized clinical trial demonstrated that dual-site aiTBS significantly reduced suicidal ideation compared to single-site treatment in adolescents.

  • 4

    The study adhered to ethical guidelines and involved rigorous participant selection, ensuring a reliable assessment of aiTBS efficacy.

  • 5

    Findings suggest that dual-site aiTBS may offer a novel intervention for rapidly addressing suicidal thoughts in adolescents with MDD.

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