Combination Therapy in Myopia Control
Which children, when, and why?
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By
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Jan Roelof Polling
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Trine Møldrup Jakobsen
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Leila Sara Eppenberger
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Andrzej Grzybowski
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August 14, 2026
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1
Combination therapy is increasingly considered for myopia control, particularly when a child shows ongoing progression despite monotherapy.
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2
Not all children with progressing myopia require combination therapy; many can be effectively managed with monotherapy.
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3
Children at higher risk for myopia progression include those who are younger, have rapid axial elongation, or a strong family history.
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4
Before initiating combination therapy, clinicians should audit treatment adherence and effectiveness to confirm true progression.
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5
Evidence suggests combination therapy may be beneficial, but it should not be viewed as a universal next step for all patients.
