Off-label Use of Gastrointestinal Multiplex PCR Panel for the Diagnosis of Amoebic Liver Abscess: A Three-case Pediatric Report - Takeaways - MDSpire
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Utilization of Gastrointestinal Multiplex PCR Panel for Diagnosing Amoebic Liver Abscess: A Report on Three Pediatric Cases

  • By

  • Michael Muñoz-Rosa

  • Natalia Arango-Serna

  • Juan Mesa-Monsalve

  • Alejandro Diaz-Diaz

  • October 15, 2025

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  • 1

    Amoebic liver abscess is a significant cause of morbidity and mortality in low- and middle-income countries.

  • 2

    The FilmArray Gastrointestinal panel effectively diagnosed E. histolytica in liver abscess fluid in three pediatric cases.

  • 3

    Off-label use of the multiplex PCR panel enabled rapid diagnosis and targeted therapy for amoebic liver abscess.

  • 4

    Traditional diagnostic methods for amoebic liver abscess are limited by false negatives and resource constraints.

  • 5

    Timely diagnosis and treatment adjustments led to favorable clinical outcomes in all three pediatric patients.

Original Source(s)

Off-label Use of Gastrointestinal Multiplex PCR Panel for the Diagnosis of Amoebic Liver Abscess: A Three-case Pediatric Report

  • by Michael Muñoz-Rosa, Natalia Arango-Serna, Juan Mesa-Monsalve, Alejandro Diaz-Diaz

  • October 15, 2025

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