Prevalence and Determinants of Diabetes Mellitus in 2338 Long-Term Dutch Childhood Cancer Survivors (DCCS-LATER2 Study) - Takeaways - MDSpire

Prevalence and Determinants of Diabetes Mellitus in 2338 Long-Term Dutch Childhood Cancer Survivors (DCCS-LATER2 Study)

  • By

  • Melissa Bolier

  • Demi T C de Winter

  • Marta Fiocco

  • Sjoerd A A van den Berg

  • Dorine Bresters

  • Eline van Dulmen-den Broeder

  • Margriet van der Heiden-van der Loo

  • Imo Hoefer

  • Geert O Janssens

  • Leontien C M Kremer

  • Jacqueline J Loonen

  • Marloes Louwerens

  • Heleen J van der Pal

  • Saskia M F Pluijm

  • Wim J E Tissing

  • Hanneke M van Santen

  • Andrica C H de Vries

  • Aart-Jan van der Lely

  • Marry M van den Heuvel-Eibrink

  • Sebastian J C M M Neggers

  • February 7, 2025

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  • 1

    The study assessed diabetes mellitus prevalence in 2338 childhood cancer survivors in the Netherlands, revealing significant health risks.

  • 2

    Childhood cancer survivors showed increased odds of hyperglycemia and diabetes compared to a reference cohort, emphasizing their health vulnerability.

  • 3

    Determinants of diabetes in survivors included age, BMI, family history, prior radiotherapy, hypogonadism, hypertension, and dyslipidemia.

  • 4

    The study identified a three-fold increased risk of diabetes in childhood cancer survivors, highlighting the need for early screening.

  • 5

    Implementing lifestyle interventions may help mitigate diabetes risk in childhood cancer survivors, improving their long-term health outcomes.

Original Source(s)

Prevalence and Determinants of Diabetes Mellitus in 2338 Long-Term Dutch Childhood Cancer Survivors (DCCS-LATER2 Study)

  • by Melissa Bolier, Demi T C de Winter, Marta Fiocco, Sjoerd A A van den Berg, Dorine Bresters, Eline van Dulmen-den Broeder, Margriet van der Heiden-van der Loo, Imo Hoefer, Geert O Janssens, Leontien C M Kremer, Jacqueline J Loonen, Marloes Louwerens, Heleen J van der Pal, Saskia M F Pluijm, Wim J E Tissing, Hanneke M van Santen, Andrica C H de Vries, Aart-Jan van der Lely, Marry M van den Heuvel-Eibrink, Sebastian J C M M Neggers

  • February 7, 2025

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