Evaluating the Role of Treatment Accessibility in HIV-TB Co-Infection: A Comparative Approach Using Fractional-Order Modeling - Takeaways - MDSpire

Evaluating the Role of Treatment Accessibility in HIV-TB Co-Infection: A Comparative Approach Using Fractional-Order Modeling

  • By

  • Agbata Benedict Celestine

  • Mehmet Gümüş

  • A. K. Awasthi

  • Homan Emadifar

  • Aseel Smerat

  • Bolarinwa Bolaji

  • February 14, 2026

  • 0 min

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  • 1

    Tuberculosis (TB) remains a leading infectious disease, causing approximately 1.6 million deaths globally in 2022, particularly in low-income countries.

  • 2

    HIV significantly increases the risk of developing active TB, with HIV-positive individuals being 16–27 times more likely to progress to active TB.

  • 3

    The dual burden of HIV and TB complicates treatment due to overlapping toxicities, drug interactions, and weak healthcare systems in high-burden regions.

  • 4

    Integrated approaches combining early HIV diagnosis, ART scale-up, and TB preventive therapy are essential for managing HIV-TB co-infection effectively.

  • 5

    Recent modeling studies highlight the importance of tailored interventions and healthcare capacity in reducing the burden of HIV-TB co-infection.

Original Source(s)

Evaluating the Role of Treatment Accessibility in HIV-TB Co-Infection: A Comparative Approach Using Fractional-Order Modeling

  • by Agbata Benedict Celestine, Mehmet Gümüş, A. K. Awasthi, Homan Emadifar, Aseel Smerat, Bolarinwa Bolaji

  • February 14, 2026

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